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Provencher Inc lcmodel version 6.3 software
Lcmodel Version 6.3 Software, supplied by Provencher Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/lcmodel+version+6%2E3/lcmodel+software/pm40602555-98-6-10
Average 90 stars, based on 1 article reviews
lcmodel version 6.3 software - by Bioz Stars, 2026-09
90/100 stars

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Article Title: Insights from auditory cortex for GABA+ magnetic resonance spectroscopy studies of aging.
Article Snippet: Edited by: John Foxe Abstract Changes in levels of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) may underlie aging-related changes in brain function.. GABA and coedited macromolecules (GABA+) can be measured with MEGA-PRESS magnetic resonance spectroscopy (MRS).. The current study investigated how changes in the aging brain impact the interpretation of GABA+ measures in bilateral auditory cortices of healthy young and older adults.

Article Title: Metabolite alterations in the left dorsolateral prefrontal cortex and its association with cognitive assessments in amyotrophic lateral sclerosis: A longitudinal magnetic resonance spectroscopy study.
Article Snippet: Finally, we used LCModel version 6.3 (Provencher, 2001) to analyze the water-suppressed spectra and obtain the following metabolite levels: NAA + N-acetyl aspartylglutamate (NAAG) for total NAA (tNAA), Glu + Gln for glutamine/glutamate (Glx), glycerophosphocholine (GPC) + phosphocholine (PCh) for tCho, mI, and Cr + phosphocreatine (PCr) for tCr.

Article Title: Region-specific Cerebral Metabolic Alterations in Parkinson's Disease Patients With/without Mild Cognitive Impairment.
Article Snippet: The aforementioned three metabolites were quantified using LCModel (Version 6.3, Steven Provencher, Oakville, ON, Canada).

Article Title: Multiparametric magnetic resonance imaging for detection of pathological changes in the central nervous system of a mouse model of multiple sclerosis in vivo
Article Snippet: Linear combination modelling (LCModel) version 6.3 ( s‐provencher.com/lcmodel.shtml ) was used for spectral analysis to determine metabolite concentrations.

Article Title: Neuroimaging glutamatergic mechanisms differentiating antipsychotic treatment-response
Article Snippet: Data were analyzed using LCModel version 6.3 ( http://s-provencher.com/lcmodel.shtml ).

Article Title: Multiparametric magnetic resonance imaging for detection of pathological changes in the central nervous system of a mouse model of multiple sclerosis in vivo.
Article Snippet: Linear combination modelling (LCModel) version 6.3 (s-provencher.com/lcmodel.shtml) was used for spectral analysis to determine metabolite concentrations.

Article Title: Chronic 3,4-Methylenedioxymethamphetamine (MDMA) Use Is Related to Glutamate and GABA Concentrations in the Striatum But Not the Anterior Cingulate Cortex
Article Snippet: Analysis software ReconFrame (GyroTools LLC, Zurich, Switzerland) and LCModel version 6.3 (Provencher, 2001).

Article Title: Detection of 2-Hydroxyglutarate by 3.0-Tesla Magnetic Resonance Spectroscopy in Gliomas with Rare IDH Mutations: Making Sense of “False-Positive” Cases
Article Snippet: A spectral analysis was performed using LCModel version 6.3 (Stephen Provencher, Oakville, ON, Canada) [ ].



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Overview of spectroscopy analysis. (a) Example of an <t>LCModel</t> Output MR Spectrum: Display of metabolites, including Inositol (Ins), Total Creatine (tCr), Gamma‐Aminobutyric Acid (GABA), N‐acetylaspartic Acid (NAA), Choline (Cho), Glutamate/Glutamine (Glu/Gln). (b) Single Subject LCModel Output with MEGA‐PRESS Spectra: Presentation of MEGA‐PRESS spectra; the red line indicates the fit, and the black line shows the edited spectrum.
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Provencher Inc lcmodel version 6.3
Overview of spectroscopy analysis. (a) Example of an <t>LCModel</t> Output MR Spectrum: Display of metabolites, including Inositol (Ins), Total Creatine (tCr), Gamma‐Aminobutyric Acid (GABA), N‐acetylaspartic Acid (NAA), Choline (Cho), Glutamate/Glutamine (Glu/Gln). (b) Single Subject LCModel Output with MEGA‐PRESS Spectra: Presentation of MEGA‐PRESS spectra; the red line indicates the fit, and the black line shows the edited spectrum.
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Overview of spectroscopy analysis. (a) Example of an LCModel Output MR Spectrum: Display of metabolites, including Inositol (Ins), Total Creatine (tCr), Gamma‐Aminobutyric Acid (GABA), N‐acetylaspartic Acid (NAA), Choline (Cho), Glutamate/Glutamine (Glu/Gln). (b) Single Subject LCModel Output with MEGA‐PRESS Spectra: Presentation of MEGA‐PRESS spectra; the red line indicates the fit, and the black line shows the edited spectrum.

Journal: Human Brain Mapping

Article Title: Exploring the Effects of Prefrontal Transcranial Direct Current Stimulation on Brain Metabolites: A Concurrent tDCS ‐ MRS Study

doi: 10.1002/hbm.70097

Figure Lengend Snippet: Overview of spectroscopy analysis. (a) Example of an LCModel Output MR Spectrum: Display of metabolites, including Inositol (Ins), Total Creatine (tCr), Gamma‐Aminobutyric Acid (GABA), N‐acetylaspartic Acid (NAA), Choline (Cho), Glutamate/Glutamine (Glu/Gln). (b) Single Subject LCModel Output with MEGA‐PRESS Spectra: Presentation of MEGA‐PRESS spectra; the red line indicates the fit, and the black line shows the edited spectrum.

Article Snippet: LCModel (Linear Combination Model, Version 6.3‐1R), a reliable and model‐free method for analyzing brain metabolites, was employed (Provencher , ).

Techniques: Spectroscopy